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The structure of an archaeal homodimeric ligase which has RNA circularization activity

The genome of Pyrococcus abyssi contains two open reading frames encoding proteins which had been previously predicted to be DNA ligases, Pab2002 and Pab1020. We show that while the former is indeed a DNA ligase, Pab1020 had no effect on the substrate deoxyoligo-ribonucleotides tested. Instead, Pab1...

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Dettagli Bibliografici
Autori principali: Brooks, Mark Adrian, Meslet-Cladiére, Laurence, Graille, Marc, Kuhn, Joëlle, Blondeau, Karine, Myllykallio, Hannu, van Tilbeurgh, Herman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492811/
https://ncbi.nlm.nih.gov/pubmed/18511537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.035493.108
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