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The structure of an archaeal homodimeric ligase which has RNA circularization activity

The genome of Pyrococcus abyssi contains two open reading frames encoding proteins which had been previously predicted to be DNA ligases, Pab2002 and Pab1020. We show that while the former is indeed a DNA ligase, Pab1020 had no effect on the substrate deoxyoligo-ribonucleotides tested. Instead, Pab1...

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Detalhes bibliográficos
Main Authors: Brooks, Mark Adrian, Meslet-Cladiére, Laurence, Graille, Marc, Kuhn, Joëlle, Blondeau, Karine, Myllykallio, Hannu, van Tilbeurgh, Herman
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492811/
https://ncbi.nlm.nih.gov/pubmed/18511537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.035493.108
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