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NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly
The Negative Elongation Factor (NELF) is a transcription regulatory complex that induces stalling of RNA polymerase II (Pol II) during early transcription elongation and represses expression of several genes studied to date, including Drosophila Hsp70, mammalian proto-oncogene junB, and HIV RNA. To...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2492738/ https://ncbi.nlm.nih.gov/pubmed/18628398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1643208 |
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