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Circulating microRNAs as stable blood-based markers for cancer detection

Improved approaches for the detection of common epithelial malignancies are urgently needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs (miRNAs) are small (≈22 nt) regulatory RNAs that are frequently dysregulated in cancer and have shown promise as tissue-based marker...

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Autori principali: Mitchell, Patrick S., Parkin, Rachael K., Kroh, Evan M., Fritz, Brian R., Wyman, Stacia K., Pogosova-Agadjanyan, Era L., Peterson, Amelia, Noteboom, Jennifer, O'Briant, Kathy C., Allen, April, Lin, Daniel W., Urban, Nicole, Drescher, Charles W., Knudsen, Beatrice S., Stirewalt, Derek L., Gentleman, Robert, Vessella, Robert L., Nelson, Peter S., Martin, Daniel B., Tewari, Muneesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492472/
https://ncbi.nlm.nih.gov/pubmed/18663219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804549105
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