Activation of the MEK – S6 pathway in high-grade ovarian cancers

The primary objective of this study is to demonstrate the activation and analyze the regulation of the MEK- S6 kinase pathway in high-grade ovarian cancer. Phospho-ERK (pERK), a direct substrate of MEK and two phosphorylation sites on the ribosomal protein, S6, Ser235/236 and Ser240/244, which are b...

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Detalhes bibliográficos
Main Authors: Ventura, Aviva P., Radhakrishnan, Sabarinath, Green, Ann, Rajaram, Sunitha K., Allen, April N., O’Briant, Kathy, Schummer, Michèl, Karlan, Beth, Urban, Nicole, Tewari, Muneesh, Drescher, Charles, Knudsen, Beatrice S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989426/
https://ncbi.nlm.nih.gov/pubmed/20661131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAI.0b013e3181e53e1c
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