Proteomic Analysis of Ovarian Cancer Cells Reveals Dynamic Processes of Protein Secretion and Shedding of Extra-Cellular Domains

BACKGROUND: Elucidation of the repertoire of secreted and cell surface proteins of tumor cells is relevant to molecular diagnostics, tumor imaging and targeted therapies. We have characterized the cell surface proteome and the proteins released into the extra-cellular milieu of three ovarian cancer...

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Autori principali: Faça, Vitor M., Ventura, Aviva P., Fitzgibbon, Mathew P., Pereira-Faça, Sandra R., Pitteri, Sharon J., Green, Ann E., Ireton, Renee C., Zhang, Qing, Wang, Hong, O'Briant, Kathy C., Drescher, Charles W., Schummer, Michèl, McIntosh, Martin W., Knudsen, Beatrice S., Hanash, Samir M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409963/
https://ncbi.nlm.nih.gov/pubmed/18560578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002425
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