Proteomic Analysis of Ovarian Cancer Cells Reveals Dynamic Processes of Protein Secretion and Shedding of Extra-Cellular Domains

BACKGROUND: Elucidation of the repertoire of secreted and cell surface proteins of tumor cells is relevant to molecular diagnostics, tumor imaging and targeted therapies. We have characterized the cell surface proteome and the proteins released into the extra-cellular milieu of three ovarian cancer...

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Detalhes bibliográficos
Main Authors: Faça, Vitor M., Ventura, Aviva P., Fitzgibbon, Mathew P., Pereira-Faça, Sandra R., Pitteri, Sharon J., Green, Ann E., Ireton, Renee C., Zhang, Qing, Wang, Hong, O'Briant, Kathy C., Drescher, Charles W., Schummer, Michèl, McIntosh, Martin W., Knudsen, Beatrice S., Hanash, Samir M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409963/
https://ncbi.nlm.nih.gov/pubmed/18560578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002425
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