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Circulating microRNAs as stable blood-based markers for cancer detection

Improved approaches for the detection of common epithelial malignancies are urgently needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs (miRNAs) are small (≈22 nt) regulatory RNAs that are frequently dysregulated in cancer and have shown promise as tissue-based marker...

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Detalhes bibliográficos
Main Authors: Mitchell, Patrick S., Parkin, Rachael K., Kroh, Evan M., Fritz, Brian R., Wyman, Stacia K., Pogosova-Agadjanyan, Era L., Peterson, Amelia, Noteboom, Jennifer, O'Briant, Kathy C., Allen, April, Lin, Daniel W., Urban, Nicole, Drescher, Charles W., Knudsen, Beatrice S., Stirewalt, Derek L., Gentleman, Robert, Vessella, Robert L., Nelson, Peter S., Martin, Daniel B., Tewari, Muneesh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492472/
https://ncbi.nlm.nih.gov/pubmed/18663219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804549105
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