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Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells.

Previous studies have indicated that scrapie infection results in the accumulation of a proteinase K-resistant form of an endogenous brain protein generally referred to as prion protein (PrP). The molecular nature of the scrapie-associated modification of PrP accounting for proteinase K resistance i...

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Bibliografiske detaljer
Main Authors: Caughey, B, Neary, K, Buller, R, Ernst, D, Perry, L L, Chesebro, B, Race, R E
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC249222/
https://ncbi.nlm.nih.gov/pubmed/1968104
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