Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells.

Previous studies have indicated that scrapie infection results in the accumulation of a proteinase K-resistant form of an endogenous brain protein generally referred to as prion protein (PrP). The molecular nature of the scrapie-associated modification of PrP accounting for proteinase K resistance i...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Caughey, B, Neary, K, Buller, R, Ernst, D, Perry, L L, Chesebro, B, Race, R E
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1968104/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1093-1101.1990
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