טוען...
Key clinical considerations for demonstrating the utility of preclinical models to predict clinical drug-induced torsades de pointes
While the QT/QTc interval is currently the best available clinical surrogate for the development of drug-induced torsades de pointes, it is overall an imperfect biomarker. In addition to low specificity for predicting arrhythmias, other issues relevant to using QT as a biomarker include (1) an appar...
שמור ב:
| מחבר ראשי: | |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2492101/ https://ncbi.nlm.nih.gov/pubmed/18536754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.222 |
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