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The failure of torcetrapib: what have we learned?

The failure of the cholesterol ester transfer protein (CETP) inhibitor, torcetrapib, has led to questions regarding whether the molecule itself or the mechanism of CETP inhibition was responsible for the adverse cardiovascular outcomes. Given the association with increases in blood pressure and plas...

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Bibliografische gegevens
Hoofdauteurs: Joy, T R, Hegele, R A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492099/
https://ncbi.nlm.nih.gov/pubmed/18536741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.248
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