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The failure of torcetrapib: what have we learned?
The failure of the cholesterol ester transfer protein (CETP) inhibitor, torcetrapib, has led to questions regarding whether the molecule itself or the mechanism of CETP inhibition was responsible for the adverse cardiovascular outcomes. Given the association with increases in blood pressure and plas...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2492099/ https://ncbi.nlm.nih.gov/pubmed/18536741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.248 |
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