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The failure of torcetrapib: what have we learned?

The failure of the cholesterol ester transfer protein (CETP) inhibitor, torcetrapib, has led to questions regarding whether the molecule itself or the mechanism of CETP inhibition was responsible for the adverse cardiovascular outcomes. Given the association with increases in blood pressure and plas...

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Detalhes bibliográficos
Main Authors: Joy, T R, Hegele, R A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492099/
https://ncbi.nlm.nih.gov/pubmed/18536741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.248
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