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Dose–response effects of sotalol on cardiovascular function in conscious, freely moving cynomolgus monkeys
BACKGROUND AND PURPOSE: The non-selective β-adrenoceptor antagonist, D,L-sotalol (sotalol) is commonly employed as a positive control during preclinical cardiovascular safety pharmacology testing, mainly because of its ability to prolong QT interval duration. However, no information appears in the l...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2492091/ https://ncbi.nlm.nih.gov/pubmed/18516073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.206 |
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