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Stopping treatment can reverse acquired resistance to letrozole
Using the intra tumoral aromatase xenograft model, we have observed that despite long lasting growth inhibition tumors eventually begin to grow during continued letrozole treatment. In cells isolated from these Long Term Letrozole Treated tumors (LTLT-Ca), ERα levels were decreased whereas signaling...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2491346/ https://ncbi.nlm.nih.gov/pubmed/18559495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5999 |
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