Construction and characterization of an infectious DNA clone and of mutants of simian immunodeficiency virus isolated from the African green monkey.

We constructed a full-length molecular clone of simian immunodeficiency virus from an African green monkey. Upon transfection, this clone directed the production of virus particles cytopathic and infectious to human CD4+ leukemia cell lines. Mutations were introduced by recombinant DNA techniques in...

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Bibliographic Details
Main Authors: Shibata, R, Miura, T, Hayami, M, Sakai, H, Ogawa, K, Kiyomasu, T, Ishimoto, A, Adachi, A
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC249103/
https://ncbi.nlm.nih.gov/pubmed/2293665
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