Construction and characterization of an infectious DNA clone and of mutants of simian immunodeficiency virus isolated from the African green monkey.

We constructed a full-length molecular clone of simian immunodeficiency virus from an African green monkey. Upon transfection, this clone directed the production of virus particles cytopathic and infectious to human CD4+ leukemia cell lines. Mutations were introduced by recombinant DNA techniques in...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Shibata, R, Miura, T, Hayami, M, Sakai, H, Ogawa, K, Kiyomasu, T, Ishimoto, A, Adachi, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249103/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2293665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.1.307-312.1990
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