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The Tyrosine Phosphorylation of Munc18c Induces a Switch in Binding Specificity from Syntaxin 4 to Doc2β

Glucose-stimulated insulin secretion is mediated by syntaxin 4-based SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein complexes and the Sec1/Munc18 protein Munc18c. Our laboratory recently reported that Munc18c-syntaxin 4 complexes are further regulated by the co...

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Autori principali: Jewell, Jenna L., Oh, Eunjin, Bennett, Sara M., Meroueh, Samy O., Thurmond, Debbie C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490795/
https://ncbi.nlm.nih.gov/pubmed/18541526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710445200
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