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Physical and Functional Interactions of Monoubiquitylated Transactivators with the Proteasome

Destabilization of activator-DNA complexes by the proteasomal ATPases can inhibit transcription by limiting activator interaction with DNA. Modification of the activator by monoubiquitylation protects the activator from this destabilization activity. In this study, we probe the mechanism of this pro...

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Библиографические подробности
Главные авторы: Archer, Chase T., Burdine, Lyle, Liu, Bo, Ferdous, Anwarul, Johnston, Stephen Albert, Kodadek, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490782/
https://ncbi.nlm.nih.gov/pubmed/18515799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803075200
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