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Activation Domain-dependent Monoubiquitylation of Gal4 Protein Is Essential for Promoter Binding in Vivo

The Saccharomyces cerevisiae Gal4 protein is a paradigmatic transcriptional activator containing a C-terminal acidic activation domain (AD) of 34 amino acids. A mutation that results in the truncation of about two-thirds of the Gal4AD (gal4D) results in a crippled protein with only 3% the activity o...

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Hlavní autoři: Archer, Chase T., Delahodde, Agnes, Gonzalez, Fernando, Johnston, Stephen Albert, Kodadek, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335349/
https://ncbi.nlm.nih.gov/pubmed/18326036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801050200
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