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Physical and Functional Interactions of Monoubiquitylated Transactivators with the Proteasome

Destabilization of activator-DNA complexes by the proteasomal ATPases can inhibit transcription by limiting activator interaction with DNA. Modification of the activator by monoubiquitylation protects the activator from this destabilization activity. In this study, we probe the mechanism of this pro...

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Main Authors: Archer, Chase T., Burdine, Lyle, Liu, Bo, Ferdous, Anwarul, Johnston, Stephen Albert, Kodadek, Thomas
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490782/
https://ncbi.nlm.nih.gov/pubmed/18515799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803075200
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