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Physical and Functional Interactions of Monoubiquitylated Transactivators with the Proteasome

Destabilization of activator-DNA complexes by the proteasomal ATPases can inhibit transcription by limiting activator interaction with DNA. Modification of the activator by monoubiquitylation protects the activator from this destabilization activity. In this study, we probe the mechanism of this pro...

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Bibliografiske detaljer
Main Authors: Archer, Chase T., Burdine, Lyle, Liu, Bo, Ferdous, Anwarul, Johnston, Stephen Albert, Kodadek, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490782/
https://ncbi.nlm.nih.gov/pubmed/18515799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803075200
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