TAp73β and DNp73β activate the expression of the pro-survival caspase-2(S)

p73, the p53 homologue, exists as a transactivation-domain-proficient TAp73 or deficient deltaN(DN)p73 form. Expectedly, the oncogenic DNp73 that is capable of inactivating both TAp73 and p53 function, is over-expressed in cancers. However, the role of TAp73, which exhibits tumour-suppressive proper...

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Bibliografske podrobnosti
Main Authors: Toh, Wen Hong, Logette, Emmanuelle, Corcos, Laurent, Sabapathy, Kanaga
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Gene Regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490756/
https://ncbi.nlm.nih.gov/pubmed/18611950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn414
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