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TAp73β and DNp73β activate the expression of the pro-survival caspase-2(S)
p73, the p53 homologue, exists as a transactivation-domain-proficient TAp73 or deficient deltaN(DN)p73 form. Expectedly, the oncogenic DNp73 that is capable of inactivating both TAp73 and p53 function, is over-expressed in cancers. However, the role of TAp73, which exhibits tumour-suppressive proper...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2490756/ https://ncbi.nlm.nih.gov/pubmed/18611950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn414 |
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