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Mutations responsible for adaptation of hepatitis A virus to efficient growth in cell culture.

Chimeric genomes of hepatitis A virus strain HM-175 were constructed from cDNA clones of the wild-type virus and its cell culture-adapted variant. RNA transcribed in vitro from each construct was assayed for infectivity by transfection of cultured cells. RNA transcribed from the wild-type cDNA clone...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Emerson, S U, McRill, C, Rosenblum, B, Feinstone, S, Purcell, R H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1991
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC248948/
https://ncbi.nlm.nih.gov/pubmed/1651411
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