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Attenuated hepatitis A virus: genetic determinants of adaptation to growth in MRC-5 cells.

A live candidate hepatitis A virus vaccine, developed from the HM-175 strain and adapted to growth in primary African green monkey kidney (AGMK) cells, was adapted to growth in MRC-5 cells. The nucleotide sequence of the MRC-5 cell-adapted virus was determined and compared with the known sequence of...

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Bibliografiska uppgifter
Huvudupphovsmän: Funkhouser, A W, Purcell, R H, D'Hondt, E, Emerson, S U
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC236273/
https://ncbi.nlm.nih.gov/pubmed/8254724
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