Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes.

With the rationale that the neuropathological similarities between scrapie and Alzheimer's disease reflect convergent pathological mechanisms involving altered gene expression, we set out to identify molecular events involved in both processes, using scrapie as a model to study the time course...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Diedrich, J F, Minnigan, H, Carp, R I, Whitaker, J N, Race, R, Frey, W, Haase, A T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1991
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1870200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.9.4759-4768.1991
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