Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes.

With the rationale that the neuropathological similarities between scrapie and Alzheimer's disease reflect convergent pathological mechanisms involving altered gene expression, we set out to identify molecular events involved in both processes, using scrapie as a model to study the time course...

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Библиографические подробности
Главные авторы: Diedrich, J F, Minnigan, H, Carp, R I, Whitaker, J N, Race, R, Frey, W, Haase, A T
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC248933/
https://ncbi.nlm.nih.gov/pubmed/1870200
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