Increased Hyaluronan and TSG-6 in Association with Neuropathologic Changes of Alzheimer’s Disease

Little is known about the extracellular matrix (ECM) during progression of AD pathology. Brain ECM is abundant in hyaluronan (HA), a non-sulfated glycosaminoglycan synthesized by HA synthases (HAS) 1–3 in a high molecular weight (MW) form that is degraded into lower MW fragments. We hypothesized tha...

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Bibliografiska uppgifter
I publikationen:J Alzheimers Dis
Huvudupphovsmän: Reed, MJ, Damodarasamy, M, Pathan, JL, Chan, CK, Spiekerman, C, Wight, TN, Banks, WA, Day, AJ, Vernon, RB, Keene, CD
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398602/
https://ncbi.nlm.nih.gov/pubmed/30507579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180797
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