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Synthesis of Indolines via a Domino Cu-Catalyzed Amidation/Cyclization Reaction

A highly efficient one-pot procedure for the synthesis of indolines and their homologues based on a domino Cu-catalyzed amidation/nucleophilic substitution reaction has been developed. Substituted 2-iodophenethyl mesylates and related compounds afforded the corresponding products in excellent yields...

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Detalhes bibliográficos
Main Authors: Minatti, Ana, Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2489202/
https://ncbi.nlm.nih.gov/pubmed/18522394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8008792
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