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Synthesis of (–)-Indolizidine 167B based on domino hydroformylation/cyclization reactions
The synthesis of (–)-Indolizidine 167B has been achieved from optically active (R)-3-(pyrrol-1-yl)hex-1-ene. The key step is a highly regioselective hydroformylation reaction and a one-pot intramolecular cyclization providing a general approach to the indolizine nucleus.
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Beilstein-Institut
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2241606/ https://ncbi.nlm.nih.gov/pubmed/18197967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1860-5397-4-2 |
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