A temperature-sensitive lesion in the small subunit of the vaccinia virus-encoded mRNA capping enzyme causes a defect in viral telomere resolution.

Using pulsed-field gel electrophoresis, we demonstrated that the temperature-sensitive (ts) conditional lethal mutant ts9383 is, at the nonpermissive temperature, defective in the resolution of concatemeric replicative intermediate DNA to linear 185-kb monomeric DNA genomes. The resolution defect wa...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Carpenter, M S, DeLange, A M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1649315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.8.4042-4050.1991
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