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The Big brain aquaporin is required for endosome maturation and Notch receptor trafficking

Activity of the big brain (bib) gene influences Notch signaling during Drosophila nervous system development. We demonstrate that Bib, which belongs to the aquaporin family of channel proteins, is required for endosome maturation in Drosophila epithelial cells. In the absence of Bib, early endosomes...

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Detalhes bibliográficos
Main Authors: Kanwar, Ritu, Fortini, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488160/
https://ncbi.nlm.nih.gov/pubmed/18510929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.04.038
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