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Ca(2+)-ATPase function is required for intracellular trafficking of the Notch receptor in Drosophila.
Maintaining high Ca(2+) concentrations in the lumen of the endoplasmic reticulum is important for protein synthesis and transport. We identified a lethal complementation group recovered in a screen for mutations that reduce Notch activity as loss-of-function alleles of the Drosophila Ca(2+)-ATPase g...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1999
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171664/ https://ncbi.nlm.nih.gov/pubmed/10545110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.21.5983 |
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