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Effect of Trimethoprim on Macromolecular Synthesis in Escherichia coli

Trimethoprim is a specific inhibitor of dihydrofolate reductase. When added to amino acid supplemented cultures of Escherichia coli, protein, ribonucleic acid (RNA), and deoxyribonucleic acid synthesis are rapidly inhibited. It is shown that thymidylate and purine synthesis must continuously occur i...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:J Bacteriol
Үндсэн зохиолчид: Miovic, Margaret, Pizer, Lewis I.
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: American Society for Microbiology (ASM) 1971
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4254117/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.106.3.856-862.1971
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