Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: Evidence of epistasis and competitive binding

DISC1 influences susceptibility to psychiatric disease and related phenotypes. Intact functions of DISC1 and its binding partners, NDEL1 and NDE1, are critical to neurodevelopmental processes aberrant in schizophrenia (SZ). Despite evidence of an NDEL1–DISC1 protein interaction, there have been no i...

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Main Authors: Burdick, Katherine E., Kamiya, Atsushi, Hodgkinson, Colin A., Lencz, Todd, DeRosse, Pamela, Ishizuka, Koko, Elashvili, Sarah, Arai, Hiroyuki, Goldman, David, Sawa, Akira, Malhotra, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486442/
https://ncbi.nlm.nih.gov/pubmed/18469341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn146
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