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Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: Evidence of epistasis and competitive binding

DISC1 influences susceptibility to psychiatric disease and related phenotypes. Intact functions of DISC1 and its binding partners, NDEL1 and NDE1, are critical to neurodevelopmental processes aberrant in schizophrenia (SZ). Despite evidence of an NDEL1–DISC1 protein interaction, there have been no i...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Burdick, Katherine E., Kamiya, Atsushi, Hodgkinson, Colin A., Lencz, Todd, DeRosse, Pamela, Ishizuka, Koko, Elashvili, Sarah, Arai, Hiroyuki, Goldman, David, Sawa, Akira, Malhotra, Anil K.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2008
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486442/
https://ncbi.nlm.nih.gov/pubmed/18469341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn146
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