Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: Evidence of epistasis and competitive binding

DISC1 influences susceptibility to psychiatric disease and related phenotypes. Intact functions of DISC1 and its binding partners, NDEL1 and NDE1, are critical to neurodevelopmental processes aberrant in schizophrenia (SZ). Despite evidence of an NDEL1–DISC1 protein interaction, there have been no i...

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Autori principali: Burdick, Katherine E., Kamiya, Atsushi, Hodgkinson, Colin A., Lencz, Todd, DeRosse, Pamela, Ishizuka, Koko, Elashvili, Sarah, Arai, Hiroyuki, Goldman, David, Sawa, Akira, Malhotra, Anil K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486442/
https://ncbi.nlm.nih.gov/pubmed/18469341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn146
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