Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-β signalling

The TGIF homoeodomain protein functions as an important negative regulator in the TGF-β signalling pathway. The inhibitory function of TGIF is executed in part through its ability to sequester the tumour suppressor cytoplasmic promyelocytic leukaemia (cPML) in the nucleus, thereby preventing the pho...

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Hlavní autoři: Faresse, Nourdine, Colland, Frédéric, Ferrand, Nathalie, Prunier, Céline, Bourgeade, Marie-Francoise, Atfi, Azeddine
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486419/
https://ncbi.nlm.nih.gov/pubmed/18511908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.109
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