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Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-β signalling
The TGIF homoeodomain protein functions as an important negative regulator in the TGF-β signalling pathway. The inhibitory function of TGIF is executed in part through its ability to sequester the tumour suppressor cytoplasmic promyelocytic leukaemia (cPML) in the nucleus, thereby preventing the pho...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2486419/ https://ncbi.nlm.nih.gov/pubmed/18511908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.109 |
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