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TRPV1-null mice are protected from diet-induced obesity

We explored a role for the capsaicin receptor TRPV1 in the regulation of feeding and body mass. On a 4.5% fat diet, wild-type and TRPV1-null mice gained equivalent body mass. On an 11% fat diet, however, TRPV1-null mice gained significantly less mass and adiposity; at 44 weeks the mean body weights...

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Hlavní autoři: Motter, Arianne L., Ahern, Gerard P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486372/
https://ncbi.nlm.nih.gov/pubmed/18503767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.05.021
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