UGT1A6 genotype-related pharmacokinetics of deferiprone (L1) in healthy volunteers

AIMS: To examine the effects of UGT1A6 polymorphisms on the pharmacokinetics of deferiprone in healthy volunteers. METHODS: Twenty-two healthy volunteers were enrolled and grouped according to UGT1A6 genotype. After an overnight fast, the subjects received a single oral dose of 25 mg kg(−1) deferipr...

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Detalhes bibliográficos
Main Authors: Limenta, Lie Michael George, Jirasomprasert, Totsapol, Tankanitlert, Jeeranut, Svasti, Saovaros, Wilairat, Prapin, Chantharaksri, Udom, Fucharoen, Suthat, Morales, Noppawan Phumala
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Pharmacogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485226/
https://ncbi.nlm.nih.gov/pubmed/18318774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03103.x
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