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Population pharmacokinetic modelling for enterohepatic circulation of mycophenolic acid in healthy Chinese and the influence of polymorphisms in UGT1A9

AIMS: To establish a population pharmacokinetic model that describes enterohepatic circulation (EHC) of mycophenolic acid (MPA) based on physiological considerations and to investigate the influence of polymorphisms of UGT1A9 on the pharmacokinetics of MPA. METHODS: Pharmacokinetic data were obtaine...

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Detaylı Bibliyografya
Asıl Yazarlar: Jiao, Zheng, Ding, Jun-jie, Shen, Jie, Liang, Hui-qi, Zhong, Long-jin, Wang, Yi, Zhong, Ming-kang, Lu, Wei-yue
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485216/
https://ncbi.nlm.nih.gov/pubmed/18279479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03109.x
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