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A screen to identify drug resistant variants to target-directed anti-cancer agents

The discovery of oncogenes and signal transduction pathways important for mitogenesis has triggered the development of target-specific small molecule anti-cancer compounds. As exemplified by imatinib (Gleevec), a specific inhibitor of the Chronic Myeloid Leukemia (CML)-associated Bcr-Abl kinase, the...

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Dettagli Bibliografici
Pubblicato in:Biol Proced Online
Autori principali: Azam, Mohammad, Raz, Tal, Nardi, Valentina, Opitz, Sarah L., Daley, George Q.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248481/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14615817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1251/bpo63
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