Structural Basis for the Regulation of Muscle Contraction by Troponin and Tropomyosin

The molecular switching mechanism governing skeletal and cardiac muscle contraction couples the binding of Ca(2+) on troponin to the movement of tropomyosin on actin filaments. Despite years of investigation, this mechanism remains unclear because it has not yet been possible to directly assess the...

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Bibliographic Details
Main Authors: Galińska-Rakoczy, Agnieszka, Engel, Patti, Xu, Chen, Jung, HyunSuk, Craig, Roger, Tobacman, Larry S., Lehman, William
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483953/
https://ncbi.nlm.nih.gov/pubmed/18514658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.04.062
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