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The C-terminus of cardiac troponin I stabilizes the Ca(2+)-activated state of tropomyosin on actin filaments
RATIONALE: Ca(2+) control of troponin-tropomyosin position on actin regulates cardiac muscle contraction. The inhibitory subunit of troponin, cardiac troponin I (cTnI) is primarily responsible for maintaining a tropomyosin conformation that prevents crossbridge cycling. Despite extensive characteriz...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834238/ https://ncbi.nlm.nih.gov/pubmed/20035081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.210047 |
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