Developmental and cell-selective variations in N-methyl-d-aspartate receptor degradation by calpain

NMDA receptors play critical roles in synaptic modulation and neurological disorders. In this study, we investigated the developmental changes in NR2 cleavage by NMDA receptor-activated calpain in cultured cortical and hippocampal neurons. Calpain activity increased with development, associated with...

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Bibliographic Details
Main Authors: Dong, Yi Na, Wu, Hai-Yan, Hsu, Fu-Chun, Coulter, Douglas A., Lynch, David R.
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483508/
https://ncbi.nlm.nih.gov/pubmed/16899064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2006.04096.x
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