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The use of biophysical methods increases success in obtaining liganded crystal structures
In attempts to determine the crystal structure of small molecule–protein complexes, a common frustration is the absence of ligand binding once the protein structure has been solved. While the first structure, even with no ligand bound (apo), can be a cause for celebration, the solution of dozens of...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
International Union of Crystallography
2007
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483471/ https://ncbi.nlm.nih.gov/pubmed/17164528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444906051869 |
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