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The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke
BACKGROUND: Macrophage elastase (MMP-12) is involved in the inflammatory process of chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate in mice the effect of MMP-12 inhibition on the inflammatory process induced by cigarette smoke (CS) or by lipopolysaccharide (LPS...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483400/ https://ncbi.nlm.nih.gov/pubmed/18493250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.180 |
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