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Roflumilast N-Oxide Prevents Cytokine Secretion Induced by Cigarette Smoke Combined with LPS through JAK/STAT and ERK1/2 Inhibition in Airway Epithelial Cells
Cigarette smoke is a major cause of chronic obstructive pulmonary disease (COPD). Airway epithelial cells and macrophages are the first defense cells against cigarette smoke and these cells are an important source of pro-inflammatory cytokines. These cytokines play a role in progressive airflow limi...
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Hlavní autoři: | , , , , , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Public Library of Science
2014
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885699/ https://ncbi.nlm.nih.gov/pubmed/24416369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085243 |
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