Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells

Phosphoinositide 3-kinase (PI3K) negatively regulates Toll-like receptor (TLR)–mediated interleukin-12 (IL-12) expression in dendritic cells (DCs). We show here that 2 signaling pathways downstream of PI3K, mammalian target of rapamycin (mTOR) and glycogen synthase kinase 3 (GSK3), differentially re...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Ohtani, Masashi, Nagai, Shigenori, Kondo, Shuhei, Mizuno, Shinta, Nakamura, Kozue, Tanabe, Masanobu, Takeuchi, Tsutomu, Matsuda, Satoshi, Koyasu, Shigeo
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481549/
https://ncbi.nlm.nih.gov/pubmed/18492954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-137430
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars