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uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs

In a minority of eukaryotic mRNAs, a small functional upstream ORF (uORF), often performing a regulatory role, precedes the translation start site for the main product(s). Here, conserved uORFs in numerous ornithine decarboxylase homologs are identified from yeast to mammals. Most have noncanonical...

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Hlavní autoři: Ivanov, Ivaylo P., Loughran, Gary, Atkins, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481320/
https://ncbi.nlm.nih.gov/pubmed/18626014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801590105
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